On selected individual-based approaches to the dynamics in multicellular systems
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Submission date: 19. Feb. 2002
published in: Polymer and cell dynamics / W. Alt (ed.)
Basel : Birkhäuser, 2003. - P. 169 - 204
MSC-Numbers: 82C22, 82C80, 92C05, 68Q80
PACS-Numbers: 87.18.-h, 87.68.+z
Keywords and phrases: individual-based models, multicellular systems
In recent years a number of different individual-based models for thespatio-temporal dynamics in multicellular organisms or parts of them have beenestablished.Individual based models (here: individuum = cell) become necessary if
(i) one is interested in understanding the organization principles in tissuesdown to length scales of the order of a cell diameter in order to link themicroscopic dynamics with a collective phenomenon,
(ii) the phenomenon under study includes variations of material or kineticproperties on length scales of the order of the cell diameter.
In this article we give a brief overview over a number of individual-based modelapproaches.