Brain networks: From structure to function and back.

  • Rolf Kötter (C. u. O. Vogt-Institut für Hirnforschung, Heinrich-Heine-Universität Düsseldorf)
A3 02 (Seminar room)


Complex brain functions are not simply the sum of modular information processing but arise from a continuous interaction of densely connected brain structures. We investigate the structural and functional characteristics of brain networks based on anatomical, electrophysiological and imaging data. These studies provide evidence of a consistent, but non-trivial coupling of structure, function and plasticity of the brain. I will show examples of how this coupling can be used to understand the network mechanisms that generate functional observables and, vice versa, to characterize the anatomy that underlies such mechanisms.

- Passingham R.E., Stephan K.E., Kötter R. (2002) The anatomical basis of functional localization in the cortex. Nature Rev. Neurosci. 3: 606-616.
- Stone J.V., Kötter R. (2002) Making connections about brain connectivity. Trends Cogn. Sci. 6: 327-328.
- Kötter R., Stephan K.E. (2003) Network participation indices: Characterizing component roles for information processing in neural networks. Neural Networks 16: 1261-1275.
- Kötter R. (2004) Online retrieval, processing, and visualization of primate connectivity data from the CoCoMac database. Neuroinformatics 2: 127-144.
- Sporns O. & Kötter R. (2004) Motifs in brain networks. PLoS Biol. 2: 1910-1918.