Brain networks: From structure to function and back.
- Rolf Kötter (C. u. O. Vogt-Institut für Hirnforschung, Heinrich-Heine-Universität Düsseldorf)
Abstract
Complex brain functions are not simply the sum of modular information processing but arise from a continuous interaction of densely connected brain structures. We investigate the structural and functional characteristics of brain networks based on anatomical, electrophysiological and imaging data. These studies provide evidence of a consistent, but non-trivial coupling of structure, function and plasticity of the brain. I will show examples of how this coupling can be used to understand the network mechanisms that generate functional observables and, vice versa, to characterize the anatomy that underlies such mechanisms.
References:
- Passingham R.E., Stephan K.E., Kötter R. (2002) The anatomical basis of functional localization in the cortex. Nature Rev. Neurosci. 3: 606-616.
- Stone J.V., Kötter R. (2002) Making connections about brain connectivity. Trends Cogn. Sci. 6: 327-328.
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- Kötter R. (2004) Online retrieval, processing, and visualization of primate connectivity data from the CoCoMac database. Neuroinformatics 2: 127-144.
- Sporns O. & Kötter R. (2004) Motifs in brain networks. PLoS Biol. 2: 1910-1918.
