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We have decided to discontinue the publication of preprints on our preprint server as of 1 March 2024. The publication culture within mathematics has changed so much due to the rise of repositories such as ArXiV (www.arxiv.org) that we are encouraging all institute members to make their preprints available there. An institute's repository in its previous form is, therefore, unnecessary. The preprints published to date will remain available here, but we will not add any new preprints here.

MiS Preprint
40/2014

A general solution of the Wright-Fisher model of random genetic drift

Tat Dat Tran, Julian Hofrichter and Jürgen Jost

Abstract

We introduce a general solution concept for the Fokker-Planck (Kolmogorov) equation representing the diffusion limit of the Wright-Fisher model of random genetic drift for an arbitrary number of alleles at a single locus. This solution will continue beyond the transitions from the loss of alleles, that is, it will naturally extend to the boundary strata of the probability simplex on which the diffusion is defined. This also takes care of the degeneracy of the diffusion operator at the boundary. We shall then show the existence and uniqueness of a solution. From this solution, we can readily deduce information about the evolution of a Wright-Fisher population.

Received:
Mar 21, 2014
Published:
Apr 7, 2014

Related publications

inJournal
2019 Repository Open Access
Tat Dat Tran, Julian Hofrichter and Jürgen Jost

A general solution of the Wright-Fisher model of random genetic drift

In: Differential equations and dynamical systems, 27 (2019) 4, pp. 467-492