MiS Preprint Repository
We have decided to discontinue the publication of preprints on our preprint server end of 2024. The publication culture within mathematics has changed so much due to the rise of repositories such as ArXiV (www.arxiv.org) that we are encouraging all institute members to make their preprints available there. An institute's repository in its previous form is, therefore, unnecessary. The preprints published to date will remain available here, but we will not add any new preprints here.
On the possible use of ICA to identify synaptic inputs from observations of several neurons
Pando Georgiev and Henry TuckwellAbstract
We consider the problem of separating and determining the time courses of various synaptic input currents from simultaneous recordings of the time courses of membrane potentials, including spikes, of several neurons. Employing a suitable mathematical model the method involves the differentiation of potentials and the use of ICA to determine the relative strengths of various synaptic inputs. At the same time the waveforms of those input currents are recovered. We illustrate the application to nonlinear point models with deterministic and stochasticinput currents,using a single-component Fitzhugh-Nagumo approximation.
- Received:
- 03.12.04
- Published:
- 03.12.04
- Keywords:
- ica for de's, synaptic input, neuron